{"id":209,"date":"2016-06-01T12:02:57","date_gmt":"2016-06-01T12:02:57","guid":{"rendered":"https:\/\/blogs.mathworks.com\/headlines\/?p=209"},"modified":"2016-07-25T10:22:47","modified_gmt":"2016-07-25T10:22:47","slug":"using-matlab-to-catch-athletes-who-cheat","status":"publish","type":"post","link":"https:\/\/blogs.mathworks.com\/headlines\/2016\/06\/01\/using-matlab-to-catch-athletes-who-cheat\/","title":{"rendered":"Using MATLAB to catch athletes who cheat"},"content":{"rendered":"<p>The difference between\u00a0<a href=\"http:\/\/www.wired.com\/2012\/07\/10-incredibly-close-olympic-finishes\/\" target=\"_blank\">a gold and a silver<\/a>\u00a0medal in many Olympic races is only a fraction of a second. This pushes athletes, and the networks that support them, to look for ways to get even the slightest edge, often through unethical approaches.<\/p>\n<p>On May 17<sup>th<\/sup>, <em><a href=\"https:\/\/www.washingtonpost.com\/sports\/olympics\/dozens-of-athletes-face-ban-from-rio-olympics-in-ioc-doping-crackdown\/2016\/05\/17\/16c1360e-1c58-11e6-8c7b-6931e66333e7_story.html\" target=\"_blank\">The Washington Post<\/a> <\/em>reported that 31 Olympic athletes recently tested positive in doping reanalysis. The International Olympic Committee specifically retested samples from\u00a0454\u00a0athletes from the Beijing 2008 Olympics who\u00a0are considered likely to compete in the upcoming Rio 2016 Olympics.<\/p>\n<p>The 31 athletes who\u00a0failed the reanalysis hail from <a href=\"http:\/\/www.nytimes.com\/2016\/05\/25\/sports\/olympics\/russia-names-14-implicated-in-doping-at-the-2008-olympic-games-in-beijing.html?_r=0\" target=\"_blank\">12 different countries and competed in six sports<\/a>. Last week, 14 athletes from Russia were identified,\u00a0including ten who\u00a0had\u00a0<a href=\"http:\/\/www.cbsnews.com\/news\/14-russian-athletes-beijing-olympics-retest-positive-doping\/\" target=\"_blank\">medaled<\/a> in the Beijing Olympics. These athletes could be <a href=\"http:\/\/www.thetimes.co.uk\/article\/russia-likely-to-be-banned-for-rio-olympics-after-14-more-cheats-from-beijing-are-exposed-nt9rf3gwj\" target=\"_blank\">stripped of their medals<\/a> in addition to being banned from future Olympic competitions.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" width=\"220\" height=\"330\" class=\"alignnone size-full wp-image-215\" src=\"https:\/\/blogs.mathworks.com\/headlines\/files\/feature_image\/track.jpg\" alt=\"843022.TIF\" \/><\/p>\n<h2><span style=\"color: #e89400;\"><strong>Using MATLAB to catch athletes who cheat<\/strong><\/span><\/h2>\n<p>To avoid discovery, athletes have moved away from heavy steroid use. Now, synthetic hormones and <a href=\"https:\/\/en.wikipedia.org\/wiki\/Erythropoietin\" target=\"_blank\">erythropoietin<\/a>\u00a0(EPO) are more common. EPO allows the blood to have a greater carrying capacity for oxygen. <a href=\"http:\/\/www.newsweek.com\/how-do-drug-cheats-sports-get-away-it-364691\" target=\"_blank\">Some athletes take small amounts\u2014known as \u201cmicrodosing\u201d\u2014to evade detection and still get the benefits.<\/a><\/p>\n<p>EPO is nearly impossible to detect in normal blood and urine tests, and synthetic hormones masquerade as regular hormones in athletes. In the case of microdosing, detection of minuscule amounts may not be enough to prove the use of doping in athletes, since \u201cnormal\u201d varies on a person-by-person basis.<\/p>\n<p>Researchers from World Anti-Doping Agency (WADA) have turned to <a href=\"https:\/\/en.wikipedia.org\/wiki\/Bayesian_statistics\" target=\"_blank\">Bayesian statistics<\/a> to find changes that deviate from the \u201cnormal\u201d for any given athlete.<\/p>\n<p style=\"padding-left: 30px;\">\u201cThey soon realized that, even if they couldn\u2019t detect the drugs themselves, they could often detect the effects of the drugs\u2014changes in the levels and ratios of young and mature red blood cells, for example,\u201d says <a href=\"http:\/\/www.newyorker.com\/news\/sporting-scene\/using-math-to-catch-athletes-who-dope\" target=\"_blank\">Alex Hutchinson for <em>The New Yorker<\/em><\/a>. \u201cEven better, this approach could flag athletes who were turning to so-called autologous blood doping, extracting and later reinjecting their own blood without actually using any illicit substances.\u201d<\/p>\n<p>A Bayesian solution looks at previous results to predict normal results going forward, and can flag those results that fall outside the expected range. In order to do this, testing centers create an athlete biological passport (ABP): a record in which results of doping tests are collected over a period of time and used to calculate thresholds of suspicious results for each individual athlete.<\/p>\n<ul>\n<li>Researchers from the Swiss Laboratory for Doping Analyses and WADA used a\u00a0Bayesian approach to highlight the validity of a blood passport for elite athletes:<\/li>\n<\/ul>\n<p style=\"padding-left: 30px;\">\u201cIn the fight against blood doping, the interpretation of the measured levels of blood markers is based on either population-derived reference ranges or the previous test history of the individual under scrutiny. In this report, we demonstrate how an empirical hierarchical Bayesian model can be used to unify both approaches,\u201d excerpt from the paper<em><span style=\"text-decoration: underline;\"> <a href=\"http:\/\/lpr.oxfordjournals.org\/content\/early\/2008\/01\/11\/lpr.mgm042.full.pdf\" target=\"_blank\">A forensic approach to the interpretation of blood doping markers.<\/a><\/span><\/em><\/p>\n<p style=\"padding-left: 30px;\">The Bayesian network utilized in this research was implemented in <a href=\"https:\/\/www.mathworks.com\/products\/matlab\/\" target=\"_blank\">MATLAB<\/a> with <a href=\"https:\/\/www.mathworks.com\/products\/statistics\/\" target=\"_blank\">Statistics Toolbox<\/a>. The\u00a0researchers\u00a0also created a standalone application with <a href=\"https:\/\/www.mathworks.com\/products\/compiler\/\" target=\"_blank\">MATLAB Compiler<\/a>, in order to provide access to the tool to other researchers.<\/p>\n<ul>\n<li>The Swiss Laboratory for Doping Analyses examined the ABPs of athletes from different countries, a process detailed in the paper <span style=\"text-decoration: underline;\"><em><a style=\"text-decoration: underline;\" href=\"http:\/\/www.clinchem.org\/content\/57\/5\/762.long\" target=\"_blank\">Prevalence of Blood Doping in Samples Collected from Elite Track and Field Athletes<\/a>.<\/em><\/span>\u00a0The\u00a0paper outlines how\u00a0researchers performed rigorous statistical analysis using MATLAB with Statistics Toolbox.\u00a0In addition to the expected difference between endurance and non-endurance athletes, this study found nationality to be the major factor in the prevalence of expected doping.<\/li>\n<\/ul>\n<h2><span style=\"color: #e89400;\"><strong>What will result from recent testing revelations?<\/strong><\/span><\/h2>\n<p>Will individual athletes be banned from the upcoming Olympics or entire teams? Will medals be stripped from athletes? While the outcome of the recent testing revelations is uncertain, we can be certain that as new methods evolve to defeat the testing procedures, new tests will be designed to catch athletes who cheat.<\/p>\n","protected":false},"excerpt":{"rendered":"<div class=\"overview-image\"><img decoding=\"async\"  class=\"img-responsive\" src=\"https:\/\/blogs.mathworks.com\/headlines\/files\/feature_image\/track.jpg\" onError=\"this.style.display ='none';\" \/><\/div>\n<p>The difference between\u00a0a gold and a silver\u00a0medal in many Olympic races is only a fraction of a second. This pushes athletes, and the networks that support them, to look for ways to get even the&#8230; <a class=\"read-more\" href=\"https:\/\/blogs.mathworks.com\/headlines\/2016\/06\/01\/using-matlab-to-catch-athletes-who-cheat\/\">read more >><\/a><\/p>\n","protected":false},"author":138,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.mathworks.com\/headlines\/wp-json\/wp\/v2\/posts\/209"}],"collection":[{"href":"https:\/\/blogs.mathworks.com\/headlines\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.mathworks.com\/headlines\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.mathworks.com\/headlines\/wp-json\/wp\/v2\/users\/138"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.mathworks.com\/headlines\/wp-json\/wp\/v2\/comments?post=209"}],"version-history":[{"count":22,"href":"https:\/\/blogs.mathworks.com\/headlines\/wp-json\/wp\/v2\/posts\/209\/revisions"}],"predecessor-version":[{"id":400,"href":"https:\/\/blogs.mathworks.com\/headlines\/wp-json\/wp\/v2\/posts\/209\/revisions\/400"}],"wp:attachment":[{"href":"https:\/\/blogs.mathworks.com\/headlines\/wp-json\/wp\/v2\/media?parent=209"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.mathworks.com\/headlines\/wp-json\/wp\/v2\/categories?post=209"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.mathworks.com\/headlines\/wp-json\/wp\/v2\/tags?post=209"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}